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Acupuncture as a Treatment Modality for the Management of Cancer Pain: The State of the Science

Anne Seton Hopkins Hollis

acupressure, acupuncture, complementary and alternative therapies
ONF 2010, 37(5), E344-E348. DOI: 10.1188/10.ONF.E344-E348

Purpose/Objectives: To explore the current state of the science regarding acupuncture as a treatment modality for cancer pain.

Data Sources: PubMed and CINAHL® databases were searched, as were Web sites from the National Cancer Institute, the National Institute of Health's Complementary and Alternative Medicine Program, and the American Cancer Society.

Data Synthesis: This article synthesizes nine years of published research on the use of acupuncture as an adjunct treatment for the management of cancer pain.

Conclusions: Findings suggest a lack of level I evidence regarding the use of acupuncture as a cancer pain treatment modality. The majority of evidence is level III or higher; therefore, causality cannot be inferred.

Implications for Nursing: Future research should focus on level I and level II evidence, controlling for variables to strengthen validity, and addressing sample size to enhance the generalizability of results. Nurses should be knowledgeable about the state of the science evidence available to assist patients in making educated decisions.

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    Alimi, D., Rubino, C., Pichard-Léandri, E., Fermand-Brulé, S., Dubreuil-Lemaire, M. L., & Hill, C. (2003). Analgesic effect of auricular acupuncture for cancer pain: A randomized, blinded, controlled trial. Journal of Clinical Oncology, 21, 4120-4126.
    Bardia, A., Barton, D., Prokop, L., Bauer, B., & Moynihan, T. (2006). Efficacy of complementary and alternative medicine therapies in relieving cancer pain: A systematic review. Journal of Clinical Oncology, 24, 5457-5463. doi: 10.1200/JCO.2006.08.3725
    Carlsson, C., & Sjolund, B. (2001). Acupuncture for chronic low back pain: A randomized placebo-controlled study with long-term follow-up. Clinical Journal of Pain, 17, 296-305.
    Cassileth, B., Trevisan, C., & Gubili, J. (2007). Complementary therapies for cancer pain. Current Pain and Headache Reports, 11, 265-269. doi: 10.1007/s11916-007-0202-8
    Dang, W., & Yang, J. (1998). Clinical study on acupuncture treatment of stomach carcinoma pain. Journal of Traditional Chinese Medicine, 18, 31-38.
    Filshie, J., & Redman, D. (1985). Acupuncture and malignant pain problems. European Journal of Surgical Oncology, 11, 389-394.
    Konkimalla, V. B., & Efferth, T. (2007). Evidence-based Chinese medicine for cancer therapy. Journal of Ethnopharmacology, 116, 207-210. doi: 10.1016/j.jep.2007.12.009
    Lee, H. J., Lee, J. H., Lee, E. O., Lee, H. J. Kim, K. H., Kim, S. H., … Kim, S. H. (2009). Substance P and beta-endorphin mediate electro-acupuncture induced analgesia in mouse cancer pain model. Acupuncture and Electro-Therapeutics Research, 34, 27-40.
    Levy, M., Chwistek, M., & Mehta, R., (2008). Management of chronic pain in cancer survivors. Cancer Journal, 14, 401-409.
    Lu, W., Dean-Clower, E., Doherty-Gilman, A., & Rosenthal, D. (2008). The value of acupuncture in cancer care. Hematology/Oncology Clinics of North America, 22, 631-648. doi: 10.1016/j.hoc.2008.04.005
    Mansky, P., & Wallerstedt, D. (2006). Complementary medicine in palliative care and cancer symptom management. Cancer Journal, 12, 425-431. doi: 10.1097/00130404-200609000-00011
    Minton, O., & Higginson, I. (2007). Electroacupuncture as an adjunctive to control neuropathic pain in patients with cancer. Journal of Pain and Symptom Management, 33, 115-117.
    National Center for Complementary and Alternative Medicine. (2009). Acupuncture: An introduction. Retrieved from
    Pan, C., Morrison, S., Ness, J., Fugh-Berman, A., & Leipzig, R. (2000). Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life. A systematic review. Journal of Pain and Symptom Management, 20, 374-387. doi: 10.1016/S0885-3924(00)00190-1
    Wells, M., Sarna, L., Cooley, M., Brown, J., Chernecky, C., Williams, R.,… Danao, L. (2007). Use of complementary and alternative medicine therapies to control symptoms in women living with lung cancer. Cancer Nursing, 30, 45-55. doi: 10.1097/00002820-200701000-00008
    Wong, R., & Sagar, S. (2006). Acupuncture treatment for chemotherapy-induced peripheral neuropathy. Acupuncture in Medicine, 24, 87-91.
    Xia, Y. Q., Zhang, D., & Yang, C. X. (1986). An approach to the effect on tumors of acupuncture in combination with radiotherapy or chemotherapy. Journal of Traditional Chinese Medicine, 6, 23-26.
    Xu, S., Liu, Z., & Li, Y. (1995). Treatment of cancerous abdominal pain by acupuncture: A report of 92 cases. Journal of Traditional Chinese Medicine, 15, 189-191.