The Emergence of Thalidomide in Treating Advanced Renal Cell Carcinoma

Laura S. Wood

Cherie Perez

Dana Monroe

ONF 2003, 30(3), 501-511. DOI: 10.1188/03.ONF.501-511

Purpose/Objectives: To review standard and investigational treatments in advanced renal cell carcinoma, with a focus on thalidomide.

Data Sources: Published articles, conference proceedings, treatment guidelines, and textbooks.

Data Synthesis: The prognosis for advanced renal cell carcinoma when treated with standard regimens is poor; therefore, new treatments are needed.

Conclusions: Treatment with thalidomide, alone and in combination with other therapies, may improve survival for patients with advanced renal cell carcinoma.

Implications for Nursing: Proactive management of adverse effects associated with thalidomide, alone and in combination, may increase patient tolerance and compliance.

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