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Clinical Q&A

Barbara Holmes Gobel
CJON 2003, 7(1), 104-108 DOI: 10.1188/03.CJON.104-108

Question: What is the appropriate way to dose carboplatin (Paraplatin ®, Bristol-Myers Squibb, Princeton, NJ) when patients’ creatinine clearance (CrCl) are decreased or a concern exists about patients’ hematologic status (e.g., decreasing the dose after using a standard area under the curve [AUC] dosing or by choosing a lower AUC)?

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