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Epirubicin Hydrochloride

Kathy Wilkinson
Christy Dolbey
CJON 2002, 6(4), 247-248 DOI: 10.1188/02.CJON.247-248

Epirubicin is a semisynthetic derivative of daunorubicin and the 4'-epimer of doxorubicin. Its action is unclear; it forms a complex with DNA, causing inhibition of nucleic acid and protein synthesis. The drug appears to interfere with replication and transcription of DNA, leading to cell death.

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