Background: The multifaceted origins of cancer are related to the dynamic interface between the human body and the environment. It is estimated that as many as 60% of cancers arise from environmental exposures.

Objectives: This article describes potential risks for exposure to radon, arsenic, pesticides, and antineoplastic agents, which can lead to the development of cancer.

Methods: The authors performed a review of the literature on environmental exposures and their relationship to the development of cancer.

Findings: Environmental factors are abundant in the home, workplace, and environment. Nurses can lead campaigns to educate the public about environmental risk factors and their effects on the development of cancer.