Human papillomavirus (HPV) is commonly found on the cervix. However, new sites of the virus have emerged during the past 10 years, including the oropharynx in both sexes and the anus in men. According to Senkomago et al. (2019), 34,800 cancers reported annually in the United States from 2012 to 2016 were attributable to HPV. Of these cases, 92% were attributable to types of HPV that are targeted by the 9-valent vaccine (Senkomago et al., 2019). The role of the oncology nurse in HPV prevention begins with the education of patients and their family members regarding updated vaccination information.