Please login (Members) to view content or (Nonmembers) this article.
(4 votes)
Advanced Practice
NCPD Article
Adrenal Insufficiency: Immune Checkpoint Inhibitors and Immune-Related Adverse Event Management
CJON 2020, 24(3), 240-243 DOI: 10.1188/20.CJON.240-243
Adrenal insufficiency (AI) is a potential immune-related adverse event (irAE) of immunotherapy (e.g., checkpoint inhibitor). If not identified and treated promptly, AI can be life-threatening. Unlike other irAEs, AI may be irreversible, requiring long-term glucocorticoid and mineralocorticoid replacement. Provider and patient education are essential in the management of immune checkpoint inhibitor–induced AI.
AT A GLANCE
- Treatment with immunotherapy may lead to irAEs, such as AI.
- Glucocorticoid and mineralocorticoid replacement may be required in patients with AI.
- To manage AI over time, advanced practice RNs must be aware of its signs and symptoms.
Members Only
Access to this article is restricted. Please login to view the full article.