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Hematology and Depression Levels: Examining Correlated Factors Among Hospitalized Patients

Xiang Liu
Carrie Moore
Kathy Wanstall
Kent Armeson
Teresa Kelechi
CJON 2019, 23(4), 423-429 DOI: 10.1188/19.CJON.423-429

Background: Depression in patients with cancer negatively influences physical symptoms, treatment success, coping, and quality of life (QOL), and is associated with increased mortality.

Objectives: This study investigated the prevalence of depression and explored fatigue, QOL, and pain that is associated with depression in patients on first admission to a hematologic oncology unit.

Methods: This descriptive study measured depression, QOL, and fatigue with the Patient Health Questionnaire–9, the Functional Assessment of Cancer Therapy (FACT)–General, and the FACT–Anemia scale, respectively. Pain levels were examined with a numeric rating scale.

Findings: 58 patients participated; 17 reported moderate to severe depression, which highly correlated with fatigue, QOL, and pain. Among all factors, multivariate analysis showed that fatigue, particularly the physical domain of fatigue, has the strongest reverse correlation with depression.

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