Cancer chemoprevention involves the use of synthetic and biologic agents as targeted therapies for disease prevention, reduction, or suppression. Mechanisms of blocking or suppressing cancer-related pathways include processes of carcinogenesis, chronic inflammatory responses, DNA modulation, and signal transduction. This column provides an update on pharmacologic agents and nursing considerations for chemoprevention.

AT A GLANCE

• Chemoprevention as primary, secondary, and tertiary strategies can prevent or delay the growth of cancer. 
• A review of current and newer mechanisms of chemoprevention is discussed.
• Oncology nurses can provide education and support for cancer chemoprevention for patients and families.