Percutaneous Nephrostomy Infusion: Nursing Considerations for Treatment of Upper Urinary Tract Urothelial Carcinoma

Eryn Draganski

Ellen Sterman

Kathy Morris

percutaneous nephrostomy, urinary tract urothelial carcinoma, ureter, kidney
CJON 2017, 21(6), 759-761. DOI: 10.1188/17.CJON.759-761

An intrarenal approach using a percutaneous nephrostomy tube is a novel method to deliver chemotherapy and biotherapy to patients with upper urinary tract urothelial carcinoma. A paucity of evidence exists regarding basic nursing implications for this unique treatment option. This column will provide suggested guidelines to administer intrarenal treatment via a percutanous nephrostomy tube.


  • Upper urinary tract urothelial carcinoma may be treated using a topical approach, including instillation of chemotherapy/
  • biotherapy agents through a percutaneous nephrostomy tube.
  • Nursing implications of instillation directly into the renal pelvis and ureter are discussed, including care and safe handling.
  • References and resources are provided to guide nurses who seek additional information on this practice.
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