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Self-Reported Distress: Adult Acute Leukemia Survivors During and After Induction Therapy

Joanne L. Lester
Robin Stout
Kara Crosthwaite
Barbara L. Andersen
CJON 2017, 21(2), 211-218 DOI: 10.1188/17.CJON.211-218

Background: Data suggest that acute leukemia survivors experience moderate to severe distress that does not significantly decline from diagnosis through survivorship.

Objectives: The purpose of this study is to assess acute leukemia survivors’ level and source of self-reported distress from active cancer treatment through six months post-treatment.

Methods: A cross-sectional group-comparison design was used. Male (n = 60) and female (n = 40) survivors aged 19–84 years were accrued from a National Cancer Institute–designated cancer center. Patients were sampled at four time points: during induction therapy, at completion, and at three and six months after the end of induction therapy. Distress was self-reported using the Distress Thermometer and its 38-item Problem List (PL). Analysis of variance and chi-square determined relationships among distress scores, PL endorsements, subscale scores, and time groups.

Findings: Self-reported distress was elevated for all groups. Highest distress scores were found during induction therapy.

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