Fosaprepitant dimeglumine (Emend IV®) is an IV antiemetic that may be beneficial to patients receiving highly emetogenic regimens. Aprepitant (Emend®) is an oral medication that is administered for three consecutive days, whereas fosaprepitant is a single-dose IV medication that is administered on the day of chemotherapy for 20–30 minutes (depending on the IV access type). Fosaprepitant may be useful, yet it can also present a risk for hypersensitivity reactions and phlebitis. Oncology nurses must be aware of the signs and symptoms of these potential adverse events to properly care for their patients.
At a Glance
- When used before emetogenic chemotherapy regimens, fosaprepitant dimeglumine (Emend IV®) may help to prevent acute and delayed nausea and vomiting.
- Infusion site adverse events related to fosaprepitant may include phlebitis, erythema, pain, swelling, and local reaction.
- Hypersensitivity reactions with the use of fosaprepitant are rare.