Fecal Microbiota Transplantation in Patients With Cancer Undergoing Treatment

Fecal microbiota transplantation (FMT) is a technique used to restore the normal body flora to the gut in cases of Clostridium difficile infection (CDI). It involves instillation of the stool of a healthy donor through a nasogastric tube or colonoscopy into the gastrointestinal tract of the patient. More research is needed to determine the parameters of FMT use in patients with cancer.

At a Glance

• CDI is common in patients with cancer because of the frequent use of broad-spectrum antibiotics that can alter the normal microbiota in the gastrointestinal tract.
• CDI reoccurs frequently and can be difficult to treat.
• CDI can delay continued treatment, prolong hospitalizations, and greatly affect a patient’s quality of life.