Advanced Practice Nursing Issues

Fecal Microbiota Transplantation in Patients With Cancer Undergoing Treatment

Lisa Blackburn

Andrea Bales

Mary Caldwell

Lee Cordell

Susan Hamilton

Haley Kreider

CJON 2015, 19(1), 111-114. DOI: 10.1188/15.CJON.111-114

Fecal microbiota transplantation (FMT) is a technique used to restore the normal body flora to the gut in cases of Clostridium difficile infection (CDI). It involves instillation of the stool of a healthy donor through a nasogastric tube or colonoscopy into the gastrointestinal tract of the patient. More research is needed to determine the parameters of FMT use in patients with cancer.

At a Glance

  • CDI is common in patients with cancer because of the frequent use of broad-spectrum antibiotics that can alter the normal microbiota in the gastrointestinal tract.
  • CDI reoccurs frequently and can be difficult to treat.
  • CDI can delay continued treatment, prolong hospitalizations, and greatly affect a patient’s quality of life.
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