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African American Health Disparities in Lung Cancer

Pauline M. Green
Suzy Guerrier-Adams
Priscilla O. Okunji
Deborah Schiavone
Joann E. Smith
CJON 2013, 17(2), 180-186 DOI: 10.1188/13.CJON.180-186

Lung cancer is a leading cause of cancer-related deaths in the United States and globally. African Americans experience significant differences in lung cancer incidence and mortality. Smoking is the single greatest risk for lung cancer, making smoking cessation programs a potentially fruitful approach for reducing the risk of lung cancer. Despite clinical practice guidelines that prompt nurses to advise patients to quit smoking, only a small percentage of nurses do so. Minority patients are less likely than Whites to receive smoking cessation advice. This article discusses recent findings on the pathophysiology and risks for lung cancer. The literature on smoking cessation research is examined to determine the features of successful cessation interventions. Recommendations are offered for enhancing tobacco cessation efforts in nursing practice, education, and research.

References 

Adams, P. F., Martinez, M. E., & Vickerie, J. L. (2010). Summary health statistics for the U. S. population: National Health Interview Survey, 2009. <i>Vital Health Statistics, Series 10, 248</i>, 1-115.

American Cancer Society. (2013). <i>Cigarette smoking.</i> Retrieved from <a target="_blank" href='http://www.cancer.org/acs/groups/cid/documents/webcontent/002967-pdf.pdf...

American College of Chest Physicians. (2010). Lung cancer: Large impact, little funding [Press release]. Retrieved from <a target="_blank" href='http://www.chestnet.org/accp/article/lung-cancer-large-impact-little-fun...

American Lung Association. (2010). <i>Too many cases, too many deaths: Lung cancer in African Americans.</i> Retrieved from <a target="_blank" href='http://www.lung.org/assets/documents/publications/lung-disease-data/ala-...

Andrews, J. O., Felton, G., Wewers, M. E., Waller, J., & Tingen, M. (2007). The effect of a multicomponent smoking cessation intervention in African American women residing in public housing. <i>Research in Nursing and Health, 30</i>, 45-60. doi:10.1002/nur.20174

Arheart, K. L., Lee, D. J., Dietz, N. A., Wilkinson, J. D., Clark, J. D., LeBlanc, W. G., … Fleming, L. E. (2008). Declining trends in serum cotinine levels in U. S. worker groups: The power of policy. <i>Journal of Occupational and Environmental Medicine, 50</i>(1), 57-63. doi:10.1097/JOM.0b013e318158a486

Bach, P. B., Cramer, L. D., Warren, J. L., & Begg, C. B. (1999). Racial differences in the treatment of early-stage lung cancer. <i>New England Journal of Medicine, 341</i>, 1198-1205. doi:10.1056/NEJM199910143411606

Bryant, J., Bonevski, B., Paul, C., McElduff, P., & Attia, J. (2011). A systematic review and meta-analysis of the effectiveness of behavioural smoking cessation interventions in selected disadvantaged groups. <i>Addiction, 106</i>, 1568-1585.

Buonomo, T., Carraresi, L., Rossini, M., & Martinelli, R. (2011). Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins. <i>Journal of Translational Medicine, 9</i>, 2. doi:10.1186/1479-5876-9-2

Burns, D. M., Lee, L., Shen, L. Z., Gilpin, E., Tolley, H. D., Vaughan, J., & Shanks, T. G. (1997). Cigarette smoking behavior in the United States. In National Cancer Institute, <i>Changes in cigarette-related disease risks and their implications for prevention and control</i> (NIH Pub. No. 97-4213, pp. 30-35). Retrieved from <a target="_blank" href='http://cancercontrol.cancer.gov/tcrb/monographs/8/m8_2.pdf'>http://cance...

Centers for Disease Control and Prevention. (2008). Smoking-attributable mortality, years of potential life lost, and productivity losses—United States, 2000-2004. <i>Morbidity and Mortality Weekly Report, 57</i>, 1226-1228.

Centers for Disease Control and Prevention. (2010a). Racial/ethnic disparities and geographic differences in lung cancer incidence—38 states and the District of Columbia, 1998-2006. <i>Morbidity and Mortality Weekly Report, 59</i>, 1434-1438.

Centers for Disease Control and Prevention. (2010b). Vital signs: Nonsmokers' exposure to secondhand smoke—United States, 1999-2008. <i>Morbidity and Mortality Weekly Report, 59</i>, 1141-1146.

Centers for Disease Control and Prevention. (2011a). <i>Health disparities and inequalities report—United States, 2011.</i> Retrieved from <a target="_blank" href='http://www.cdc.gov/minorityhealth/reports/CHDIR11/ExecutiveSummary.pdf'>...

Centers for Disease Control and Prevention. (2011b). <i>Health disparities in health insurance coverage.</i> Retrieved from <a target="_blank" href='http://www.cdc.gov/minorityhealth/reports/CHDIR11/FactSheets/Insurance.p...

Centers for Disease Control and Prevention. (2011c). Vital signs: Current cigarette smoking among adults aged ≥ 18 years—United States, 2005-2010. <i>Morbidity and Mortality Weekly Report, 60</i>, 1207-1212.

Chouinard, M. C., & Robichaud-Ekstrand, S. (2005). The effectiveness of a nursing inpatient smoking cessation program in individuals with cardiovascular disease. <i>Nursing Research, 54</i>, 243-254. doi:10.1097/00006199-200507000-00006

Cokkinides, V. E., Halpern, M. T., Barbeau, E. M., Ward, E., & Thun, M. J. (2005). Racial and ethnic disparities in smoking-cessation interventions: Analysis of the 2005 National Health Interview Survey. <i>American Journal of Preventive Medicine, 34</i>, 404-412. doi:10.1016/j.amepre.2008.02.003

Corbie-Smith, G., Thomas, S. B., & St. George, D. M. (2002). Distrust, race, and research. <i>Archives of Internal Medicine, 162</i>, 2458-2463.

Darby, S., Hill, D., & Doll, R. (2001). Radon: A likely carcinogen at all exposures. <i>Annals of Oncology, 12</i>, 1341-1351.

DeLancey, J. O., Thun, M. J., Jemal, A., & Ward, E. M. (2008). Recent trends in Black-White disparities in cancer mortality. <i>Cancer Epidemiology, Biomarkers and Prevention, 17</i>, 2908-2912.

Etzel, C. J., Amos, C. I., & Spitz, M. R. (2003). Risk for smoking-related cancer among relatives of lung cancer patients. <i>Cancer Research, 63</i>, 8531-8535.

Fiore, M. C., Jaén, C. R., Baker, T. B., Bailey, W. C., Benowitz, N. L., Curry, S. J., … Wewers, M. E. (2008). <i>Treating tobacco use and dependence: 2008 update.</i> Rockville, MD: U. S. Department of Health and Human Services.

Freeman, H. P. (2004). Poverty, culture, and social justice: Determinants of cancer disparities. <i>CA: A Cancer Journal for Clinicians, 54</i>, 72-75. doi:10.3322/canjclin.54.2.72

Frost, G., Darnton, A., & Harding, A. H. (2011). The effect of smoking on the risk of lung cancer mortality for asbestos workers in Great Britain (1971-2005). <i>Annals of Occupational Hygiene, 55</i>, 239-247. doi:10.1093/annhyg/meq089

Frumkin, H., & Samet, J. M. (2001). Radon. <i>CA: A Cancer Journal for Clinicians, 51</i>, 337-344. doi:10.3322/canjclin.51.6.337

Gamble, V. N. (1997). Under the shadow of Tuskegee: African Americans and health care. <i>American Journal of Public Health, 87</i>, 1773-1778. doi:10.2105/AJPH.87.11.1773

Garrett, B. E., Dube, S. R., Trsclair, A., Carabello, R. S., & Pechacek, T. F. (2011). Cigarette smoking—United States, 1965-2008. <i>Morbidity and Mortality Weekly Report, 60</i>, 109; 113.

Giovino, G. A., Sidney, S., Gfroerer, J. C., O'Malley, P. M., Allen, J. A., Richter, P. A., & Cummings, K. M. (2004). Epidemiology of menthol cigarette use. <i>Nicotine and Tobacco Research, 6</i>(Suppl. 1), S67-S81. doi:10.1080/14622203710001649696

Haiman, C. A., Stram, D. O., Wilkens, L. R., Pike, M. C., Kolonel, L. N., Henderson, B. E., & Le Marchand, L. (2006). Ethnic and racial differences in the smoking-related risk of lung cancer. <i>New England Journal of Medicine, 354</i>, 333-342. doi:10.1056/NEJMoa033250

Herbst, R. S., Heymach, J. V., & Lippman, S. M. (2008). Lung cancer. <i>New England Journal of Medicine, 359</i>, 1367-1380. doi:10.1056/NEJMra0802714

Howlader, N., Noone, A. M., Krapcho, M., Neyman, N., Aminou, R., Altekruse, S. F., … Cronin, K. A. (2012). SEER cancer statistics review, 1975-2009 (Vintage 2009 populations). Retrieved from <a target="_blank" href='http://seer.cancer.gov/csr/1975_2009_pops09/index.html'>http://seer.canc...

Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., & Forman, D. (2011). Global cancer statistics. <i>CA: A Cancer Journal for Clinicians, 61</i>, 69-90. doi:10.3322/caac.20107

Lathan, C. S., Neville, B. A., & Earle, C. C. (2006). The effect of race on invasive staging and surgery in non-small-cell lung cancer. <i>Journal of Clinical Oncology, 24</i>, 413-417. doi:10.1200/JCO.2005.02.1758

Lee, P. N. (2011). Systematic review of the epidemiological evidence comparing lung cancer risk in smokers of mentholated and unmentholated cigarettes. <i>BMC Pulmonary Medicine, 11</i>(18), 1-28.

Mechanic, L. E., Bowman, E. D., Welsh, J. A., Khan, M. A., Hagiwara, N., Enewold, L., … Harris, C. C. (2007). Common genetic variation in TP53 is associated with lung cancer risk and prognosis in African Americans and somatic mutations in lung tumors. <i>Cancer Epidemiology, Biomarkers and Prevention, 16</i>, 214-222. doi:10.1158/1055-9965.EPI-06-0790

Motohashi, S., Okamoto, Y., Yoshino, I., & Nakayama, T. (2011). Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer. <i>Clinical Immunology, 140</i>, 167-176. doi:10.1016/j.clim.2011.01.009

National Cancer Institute. (2008). <i>Smoking prevalence and lung cancer death rates. Strategies to control tobacco use in the United States: A blueprint for public health action in the 1990's update</i> (NIH Pub. No. 07-6242; pp. 85-86). Retrieved from <a target="_blank" href='http://cancercontrol.cancer.gov/tcrb/monographs/1/m1_3.pdf'>http://cance...

National Cancer Institute. (2012a). Lung cancer prevention (PDQ®): Health professional version. Retrieved from <a target="_blank" href='http://www.cancer.gov/cancertopics/pdq/prevention/lung/HealthProfessiona...

National Cancer Institute. (2012b). Lung cancer prevention (PDQ®): Patient version. Retrieved from <a target="_blank" href='http://www.cancer.gov/cancertopics/pdq/prevention/lung/Patient/page1/All...

National Cancer Institute. (2012c). What you need to know about lung cancer: Types of lung cancer. Retrieved from <a target="_blank" href='http://www.cancer.gov/cancertopics/wyntk/lung/page4'>http://www.cancer.g...

Ou, S. H., Zell, J. A., Ziogos, A., & Anton-Culver, H. (2008). Low socioeconomic status is a poor prognostic factor for survival in stage I nonsmall cell lung cancer and is independent of surgical treatment, race, and marital status. <i>Cancer, 112</i>, 2011-2020. doi:10.1002/cncr.23397

Parsons, A., Daley, A., Begh, R., & Aveyard, P. (2010). Influence of smoking cessation after diagnosis of early stage lung cancer on prognosis: Systematic review of observational studies with meta-analysis. <i>BMJ, 340</i>, b5569. doi:10.1136/bmj.b5569

Peipins, L. A., Soman, A., Berkowitz, Z., & White, M. C. (2012). The lack of paid sick leave as a barrier to cancer screening and medical care-seeking: Results from the National Health Interview Survey. <i>BMC Public Health, 12</i>, 520. doi:10.1186/1471-2458-12-520

Phillips, J. M., Cohen, M. Z., & Moses, G. (1999). Breast cancer screening and African American women: Fear, fatalism, and silence. <i>Oncology Nursing Forum, 26</i>, 561-571.

Powe, B. D. (1996). Cancer fatalism among African Americans: A review of the literature. <i>Nursing Outlook, 44</i>(1), 18-21.

Rice, V. H., & Stead, L. F. (2008). Nursing interventions for smoking cessation. <i>Cochrane Database of Systematic Reviews, 1</i>, CD001188. doi:10.1002/14651858.CD001188.pub3

Rigotti, N. A., Arnsten, J. H., McKool, K. M., Wood-Reid, K. M., Pasternak, R. C., & Singer, D. E. (1997). Efficacy of a smoking cessation program for hospital patients. <i>Archives of Internal Medicine, 157</i>, 2653-2660. doi:10.1001/archinte.1997.00440430135016

Rigotti, N. A., Munafo, M. R., & Stead, L. F. (2008). Smoking cessation interventions for hospitalized smokers: A systematic review. <i>Archives of Internal Medicine, 168</i>, 1950-1960. doi:10.1001/archinte.168.18.1950

Robles, G. I., Singh-Franco, D., & Ghin, H. L. (2008). A review of the efficacy of smoking-cessation pharmacotherapies in nonwhite populations. <i>Clinical Therapeutics, 30</i>, 800-812. doi:10.1016/j.clinthera.2008.05.010

Sarna, L. (2012). Carpe diem. <i>Nursing Research, 61</i>(1), 1-2. doi:10.1097/NNR.0b013e31824101a1

Sarna, L., Bialous, S. A., Wells, M., Kotlerman, J., Wewers, M. E., & Froelicher, E. S. (2009). Frequency of nurses' smoking cessation interventions: Report from a national survey. <i>Journal of Clinical Nursing, 18</i>, 2066-2077. doi:10.1111/j.1365-2702.2009.02796.x

Siegel, R., Naishadham, D., & Jemal, A. (2013). Cancer statistics, 2013. <i>CA: A Cancer Journal for Clinicians, 63</i>, 11-30. doi:10.3322/caac.21166

Smith, P. M., Corso, L., Brown, K. S., & Cameron, R. (2011). Nurse case-managed tobacco cessation interventions for general hospital patients: Results of a randomized clinical trial. <i>Canadian Journal of Nursing Research, 43</i>(1), 98-117.

Sun, S., Schiller, J. H., & Gazdar, A. F. (2007). Lung cancer in never smokers—A different disease. <i>Nature Reviews. Cancer, 7</i>, 778-790. doi:10.1038/nrc2190

Tzelepis, F., Paul, C. L., Walsh, R. A., McElduff, P., & Knight, J. (2011). Proactive telephone counseling for smoking cessation: Meta-analyses by recruitment channel and methodological quality. <i>Journal of National Cancer Institute, 103</i>, 922-941. doi:10.1093/jnci/djr169

Underwood, J. M., Townsend, J. S., Tai, E., Davis, S. P., Stewart, S. L., White, A., … Fairley, T. L. (2011). Racial and regional disparities in lung cancer incidence. <i>Cancer, 118</i>, 1910-1918.

U. S. Census Bureau. (2012). Poverty: Overview/highlights. Retrieved from <a target="_blank" href='http://www.census.gov/hhes/www/poverty/about/overview/index.html'>http:/...

U. S. Department of Health and Human Services. (2004). <i>The health consequences of smoking: A report of the surgeon general</i>. Atlanta, GA: Author.

U. S. Department of Health and Human Services. (2006). <i>The health consequences of involuntary exposure to tobacco smoke: A report of the surgeon general</i>. Atlanta, GA: Author.

Wakefield, M., Olver, I., Whitford, H., & Rosenfeld, E. (2004). Motivational interviewing as a smoking cessation intervention for patients with cancer: Randomized controlled trial. <i>Nursing Research, 53</i>, 396-405. doi:10.1097/00006199-200411000-00008

Zhang, X., Miao, X., Guo, Y., Tan, W., Zhou, Y., Sun, T., … Lin, D. (2006). Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. <i>Human Mutation, 27</i>(1), 110-117. doi:10.1002/humu.20277