No votes yet

Routine Health Maintenance in Patients Living With Multiple Myeloma

Elizabeth Bilotti
Charise L. Gleason
Ann McNeill
the International Myeloma Foundation Nurse Leadership Board
CJON 2011, 15(4), 25-40 DOI: 10.1188/11.S1.CJON.25-40

Patients diagnosed with multiple myeloma are living longer because of new therapeutic options. Helping patients with multiple myeloma maintain a good state of health from the time of diagnosis and throughout their therapy leads to better quality of life. However, patients with multiple myeloma are at risk for illnesses experienced by the general population and at additional risk for illnesses related to multiple myeloma and its treatment. Therefore, the International Myeloma Foundation Nurse Leadership Board (NLB) has developed practice recommendations to meet the particular needs of adult patients with multiple myeloma using evidence-based recommendations for screening and disease prevention, as well as nursing experience. The NLB recommendations are designed to address and overcome barriers to health maintenance by educating and empowering nurses and their patients.


Ahles, T.A., & Saykin, A. (2002). Cognitive effects of standard-dose chemotherapy in patients with cancer. <i>Psychosocial Issues, 19</i>, 812-820.

American Academy of Dermatology. (2011). The ABCDEs of melanoma. Retrieved from <a target="_blank" href='http://www.aad.org/public/exams/abcde.html'>http://www.aad.org/public/ex...

American Academy of Ophthalmology. (2005). <i>Preferred practice committee. Preferred Practice Pattern® guidelines. Comprehensive adult medical eye evaluation</i>. San Francisco, CA: Author.

American Cancer Society. (2006). The complete guide—Nutrition and physical activity. Retrieved from <a target="_blank" href='http://www.cancer.org/docroot/PED/content/PED_3_2X_Diet_and_Activity_Fac...

American Cancer Society. (2008). Guidelines for the early detection of cancer. Retrieved from <a target="_blank" href='http://www.cancer.org/Search/indexQueryText=Guidelines+for+the+Early+Det...

American Cancer Society. (2009). What are the risk factors for prostate cancer? Retrieved from <a target="_blank" href='http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_What_are_the_risk_f...

American Cancer Society. (2010a). What are the key statistics about breast cancer? Retrieved from <a target="_blank" href='http://www.cancer.org/Cancer/BreastCancer/DetailedGuide/breast-cancer-ke...

American Cancer Society (2010b). What are the risk factors for breast cancer? Retrieved from <a target="_blank" href='http://www.cancer.org/Cancer/BreastCancer/DetailedGuide/breast-cancer-ri...

American Cancer Society. (2010c). What are the risk factors for colorectal cancer? Retrieved from <a target="_blank" href='http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_What_are_the_risk_f...

American Cancer Society. (2011a). <i>Cancer facts and figures, 2011</i>. Retrieved from <a target="_blank" href='http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/docume...@epidemiologysurveilance/documents/document/acspc-029771.pdf</a>

American Cancer Society. (2011b). Learn about cancer: Colorectal cancer. Retrieved from <a target="_blank" href='http://www.cancer.org/Cancer/ColonandRectumCancer/DetailedGuide/colorect...

American Dental Association. (2009). Manage your oral health and oral health topics. Retrieved from <a target="_blank" href='http://www.ada.org/5624.aspx?currentTab=1'>http://www.ada.org/5624.aspx?...

American Diabetes Association. (2011). Diabetes basics. Retrieved from <a target="_blank" href='http://www.diabetes.org/diabetes-basics/?utm_source=WWW&utm_medium=Globa...

American Psychiatric Association. (2000). <i>Diagnostic and statistical manual of mental disorders</i> (4th ed.). Washington, DC: Author.

American Speech-Language-Hearing Association. (2009). Who should be screened for hearing loss? Retrieved from http://www.asha.org/public/hearing/Who-Should-be-Screened/

Badros, A.Z., Siegel, E., Bodenner, D., Zangari, M., Zeldis, J., & Barlogie, B. (2002). Hypothyroidism in patients with multiple myeloma following treatment with thalidomide. American Journal of Medicine, 112, 412-413. doi:10.1016/S0002-9343(01)01137-8

Centers for Disease Control and Prevention. (1998). Recommendations to prevent and control iron deficiency in the United States. Retrieved from http://www.cdc.gov/mmwr/pdf/rr/rr4703.pdf

Centers for Disease Control and Prevention. (2002). Iron deficiency—United States, 1999-2000. Morbidity and Mortality Weekly Reports, 51, 897-899.

Chobanian, A.V., Bakris, G.L., Black, H.R., Cushman, W.C., Green, L.A., Izzo, J., … the National High Blood Pressure Education Program Coordinating Committee. (2003). Seventh report of the joint national committee on prevention, detection, evaluation and treatment of high blood pressure. Hypertension, 42, 1206-1252. doi:10.1161/01.HYP.0000107251.49515.c2

Coleman, E., Coon, S., Hall-Barrow, J., Richards, K., Gaylor, D., & Stewart, B. (2003). Feasibility of exercise during treatment for multiple myeloma. Cancer Nursing, 26, 410-419.

Curt, G.A., Breitbartb, W., Cellac, D., Groopmand, J.E., Horninge, S.J., Itrif, L.M., … Vogelzang, N.J. (2000). Impact of cancer-related fatigue on the lives of patients: New findings from the Fatigue Coalition. Oncologist, 5, 353-360. doi:10.1634/theoncologist.5-5-353

Dimopoulos, M.A., & Eleutherakis-Papaiakovou, V. (2004). Adverse effects of thalidomide administration in patients with neoplastic diseases. American Journal of Medicine, 117, 508-515. doi:10.1016/j.amjmed.2004.03.040

Dykewicz, C.A. (2001). Summary of the guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. Clinical Infectious Diseases, 33, 139-144. doi:10.1086/321805

Ewing, J.A. (1984). Detecting alcoholism: The CAGE questionnaire. JAMA, 252, 1905-1907. doi:10.1001/jama.252.14.1905

Faiman, B., Bilotti, E., Mangan, P.A., Rogers, K., & the International Myeloma Foundation Nurse Leadership Board. (2008). Consensus statement for the management of steroid-associated side effects in patients with multiple myeloma. Clinical Journal of Oncology Nursing, 12(3, Suppl.), 53-62. doi:10.1188/08.CJON.S1.53-62

Fatourechi, V. (2009). Subclinical hypothyroidism: An update for primary care physicians. Mayo Clinic Proceedings, 84, 65-71. doi:10.4065/84.1.65

Figaro, M.K., Clayton, W., Usoh, C., Brown, K., Kassim, A., & Lakhani, V.T. (2011). Thyroid abnormalities in patients treated with lenalidomide for hematologic malignancies: Results of a retrospective case review. American Journal of Hematology, 86, 467-470. doi:10.1002/ajh.22008

Fischbach, F.T., & Dunning, M. (2004). A manual of laboratory and diagnostic testing (7th ed.). Philadelphia, PA: Lippincott Williams and Wilkins.

Frame, P.S. (1996). Developing a health maintenance schedule. In S.H. Woolf, S. Jonas, & E. Kaplan-Liss (Eds.), Health promotion and disease prevention in clinical practice (pp. 517-530). Philadelphia, PA: Lippincott Williams and Wilkins.

Gregerman, R.I. (2003). Thyroid disorders. In L.R. Barker, J.R. Burton, & P.D. Zieve (Eds.), Principles of ambulatory medicine (6th ed., pp. 1230-1252). Philadelphia, PA: Lippincott Williams and Wilkins.

Grundy, S.M., Cleeman, J.I., Merz, C.N., Brewer, J.H., Clark, L.T., Hunninghake, D.B., … the Coordinating Committee of the National Cholesterol Education Program. (2004). A summary of implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. Arteriosclerosis, Thrombosis, and Vascular Biology, 24, 1329-1330. doi:10.1161/01.ATV.0000139012.45265.e0

Herr, C., Beisswenger, C., Hess, C., Kandler, K., Suttorp, N., Welte, T., … The CAPNETZ Study Group. (2009). Suppression of pulmonary innate host defense in smokers. Thorax, 64, 144-149. doi:10.1136/thx.2008.102681

Hewitt, M., Greenfield, S., & Stovall, E. (2006). From cancer patient to cancer survivor: Lost in translation. Washington, DC: The National Academies Press.

Institute of Medicine Food and Nutrition Board. (2001). Dietary reference intakes. Retrieved from http://books.nap.edu/openbook.php?isbn=0309072794&page=290

Jemal, A., Siegel, R., Xu, J., & Ward, E. (2010). Cancer statistics, 2010. <i>CA: A Cancer Journal for Clinicians, 60</i>, 277-300.

Katodritou, E., Zervas, K., Terpos, E., & Brugnara, C. (2008). Use of erythropoiesis stimulating agents and intravenous iron for cancer and treatment related anaemia: The need for predictors and indicators of effectiveness has not abated. <i>British Journal of Haematology, 142</i>, 3-10. doi:10.1111/j.1365-2141.2008.07163.x

Katon, W., Russo, J., Sherbourne, C., Craske, M., Fan, M.Y., & Roy-Byrne, P. (2006). Incremental cost-effectiveness of a collaborative care intervention for panic disorder. <i>Psychological Medicine, 36</i>, 353-363. doi:10.1017/S0033291705006896

Killip, S., Bennett, J.M., & Chambers, M.D. (2007). Iron deficiency anemia. <i>American Family Physician, 75</i>, 671-678.

Kroenke, K.S., & Williams, J.B. (2001). The PHQ-9: Validity of a brief depression severity measure. <i>Journal of Internal Medicine, 9</i>, 606-613.

Kumar, S.K., Rajkumar, S.V., & Dispenzieri, A. (2008). Improved survival in multiple myeloma and the impact of novel therapies. <i>Blood, 111</i>, 2516-2520. doi:10.1182/blood-2007-10-116129

Marin, M., Guris, D., Chaves, S.S., Schmid, S., & Seward, J.F. (2007). Prevention of varicella. Recommendations of the Advisory Committee on Immunization Practices (ACIP). <i>Morbidity and Mortality Weekly Report, 56</i>(RR04), 1-40.

McDaniel, S.J., Musselman, D.L., Porter, M.R., Reed, D.A., & Nemeroff, C.B. (1995). Depression in patients with cancer: Diagnosis, biology and treatment. <i>Archives of General Psychiatry, 52</i>(2), 89-99.

Menon, S., Habermann, T., & Witzig, T. (2007). Lenalidomide-associated hypothyroidism. <i>Leukemia and Lymphoma, 48</i>, 2465-2467. doi:10.1080/10428190701704613

Miceli, T., Colson, K., Faiman, B., Miller, K., Tariman, J.D., and the International Myeloma Foundation Nurse Leadership Board. ((2011). Maintaining bone health in patients with multiple myeloma: Survivorship care plan of the International Myeloma Foundation Nurse Leadership Board. <i>Clinical Journal of Oncology Nursing, 15</i>(4, Suppl.), 9-23.

Millennium: The Takeda Oncology Company. ((2010). <i>Velcade® (bortezomib)</i> [Product information]. Cambridge, MA: Author.

National Cancer Institute. (2011). Surveillance Epidemiology and End Results fast facts—SEER stat fact sheets: Myeloma. Retrieved from <a target="_blank" href='http://seer.cancer.gov/statfacts/html/mulmy.html#incidence-mortality'>ht...

National Cholesterol Education Program. (2002). Third report of the National Cholesterol Education Program (NCEP) Expert Panel on the Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Final report. <i>Circulation, 106</i>, 3143-3421.

National Eye Institute. (2008 <i>Age-related eye diseases and conditions at a glance.</i> Retrieved from <a target="_blank" href='http://www.nei.nih.gov/nehep/programs/visionandaging/materials/AgeRelate...

National Eye Institute. (2010 Vision loss from eye diseases will increase as Americans age. Retrieved from <a target="_blank" href='http://www.nei.nih.gov/news/pressreleases/041204.asp'>http://www.nei.nih...

National Heart, Lung and Blood Institute. (2002, November). <i>Primary prevention of hypertension: Clinical and public health advisory from the National High Blood Pressure Education Group.</i> Retrieved from <a target="_blank" href='http://www.nhlbi.nih.gov/health/prof/hbp.pphbp.pdf'>http://www.nhlbi.nih...

National Institute of Diabetes and Digestive and Kidney Diseases. (2007). National diabetes statistics, 2007. Retrieved from <a target="_blank" href='http://diabetes.niddk.nih.gov/dm/pubs/statistics/#allages'>http://diabet...

National Institute on Alcohol Abuse and Alcoholism. (2009). Alcohol alert: Screening for alcoholism. Retrieved from <a target="_blank" href='http://pubs.niaaa.nih.gov/publications/aa08.htm'>http://pubs.niaaa.nih.g...

National Institute on Deafness and Other Communication Disorders. (2009). NIH senior health: Hearing loss. Retrieved from <a target="_blank" href='http://nihseniorhealth.gov/hearingloss/hearinglossdefined/01.html'>http:...

Nides, M. (2008). Update on pharmacologic options for smoking cessation treatment. <i>American Journal of Medicine, 121</i>(4A), S20-S31.

Nygaarde, B., Jensen, E.W., Kvetzy, J., Jarlov, A., & Faber, J. (2009). Effect of combination therapy with thyroxin (T<sub>4</sub>) and 3, 5, 3-triiodothyronine versus T4 monotherapy in patients with hypothyroidism. A double-blind, randomized cross-over study. <i>European Journal of Endocrinology, 161</i>, 895-902. doi:10.1530/EJE-09-0542

Passik, S.D., McDonald, M.V., Dugan, J.W., Edgerton, S., & Roth, A.J. (1997). Depression in cancer patients: Recognition and treatment. <i>Medscape Psychiatry and Mental Health eJournal, 2</i>(3).

Portenoy, R.K., & Itri, L.M. (1999). Cancer-related fatigue: Guidelines for evaluation and management. <i>Oncologist, 4</i>, 1-14.

Roger, V.L., Go, A.S., Lloyd-Jones, D.M., Adams, R.J., Berry, J.D., Brown, T.M., … Wylie-Rosett, J. (2011). Heart disease and stroke statistics—2011 update. <i>Circulation, 123</i>, e18-e209. doi:10.1161/CIR.0b013e3182009701

Rome, S.I., Jenkins, B.S., Lilleby, K.E., and the International Myeloma Foundation Nurse Leadership Board. (2011). Mobility and safety in the multiple myeloma survivor: Survivorship care plan of the International Myeloma Foundation Nurse Leadership Board. <i>Clinical Journal of Oncology Nursing, 15</i>(4, Suppl.), 41-52.

Smith, R.A., Cokkinides, V., & Brawley, O.W. (2009). Cancer screening in the United States, 2009: A review of the current American Cancer Society guidelines and issues in cancer screening. <i>CA: A Cancer Journal for Clinicians, 59</i>, 27-41.

Snowden, R.V. (2010). Revised prostate cancer screening guidelines: What has—and hasn't—changed. Retrieved from <a target="_blank" href='http://www.cancer.org/docroot/nws/content/nws_1_1x_revised_prostate_canc...

Staat, K., & Segatore, M. (2005). The phenomenon of chemo brain. <i>Clinical Journal of Oncology Nursing, 9</i>, 713-721. doi:10.1188/05.CJON.713-721

Stone, P., Richardson, A., Ream, E., Smith, A.G., Kerr, D.J., & Kearney, N. (2000). Cancer-related fatigue: Inevitable, unimportant, and untreatable? Results of a multi-centre patient survey. <i>Annals of Oncology, 11</i>, 971-975. doi:10.1023/A:1008318932641

Tannock, I.F., Ahles, T.A., Ganz, P.A., & van Dam, F.S. (2004). Cognitive impairment associated with chemotherapy for cancer: Report of a workshop. <i>Journal of Clinical Oncology, 22</i>, 2233-2239. doi:10.1200/JCO.2004.08.094

U.S. Preventive Services Task Force. (2010). <i>The guide to clinical preventive services, 2010-2011. Agency for Healthcare Research and Quality.</i> Retrieved from <a target="_blank" href='http://www.ahrq.gov/clinic/pocketgd1011/pocketgd1011.pdf'>http://www.ahr...

Wiersinga, W.M. (2009). Do we need still more trials on T4 and T3 combination therapy in hypothyroidism? <i>European Journal of Endocrinology, 161</i>, 955-959. doi:10.1530/EJE-09-0879

Williams, J.M. (2007). Nonpharmacologic approaches to facilitate smoking cessation. <i>University of Tennessee Advanced Studies in Pharmacy, 4</i>(8), 221-224.

Woolfe, S. (2008). Immunizations. In S.H. Woolfe, S. Jonas, & E. Kaplan-Liss (Eds.), <i>Health promotion and disease prevention in clinical practice</i> (pp. 359-434). Philadelphia, PA: Lippincott Williams and Wilkins.