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Leukemia

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Authentic Caring Occasions for Patients in Hairy Cell Leukemia Clinical Trials

Terri L. Hutchinson
CJON 2015, 19(2), E41-E46 DOI: 10.1188/15.CJON.E41-E46
Background: Rare diseases present challenges for patients, healthcare providers, and researchers. Rare disease communities exist for collaboration, dissemination of information, and to promote support for all community members. Patients with a rare disease desire to be supported through a rare...
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Clinical Challenges

Richter Syndrome: An Aggressive Transformation

Erin Streu
ONF 2015, 42(2), 200-203 DOI: 10.1188/15.ONF.200-203
A 71-year-old male patient named M.R. was diagnosed with chronic lymphocytic leukemia (CLL). At the time of diagnosis, M.R. had generalized lymphadenopathy and splenomegaly, which caused him to experience significant abdominal discomfort. M.R. was treated with six cycles of fludarabine,...
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Patient-Reported Symptoms and Quality of Life in Adults With Acute Leukemia: A Systematic Review

Ashley Leak Bryant
AnnMarie Lee Walton
Julia Shaw-Kokot
Deborah K. Mayer
Bryce B. Reeve
ONF 2015, 42(2), E91-E101 DOI: 10.1188/15.ONF.E91-E101
Purpose/Objectives: Systematically summarize findings from research conducted on adult acute leukemia survivors as they relate to symptoms and quality of life (QOL). Data Sources: Systematic review of the literature from 1990–2013 found in the PubMed, PsycINFO®, EMBASE, and CINAHL® databases, as...
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Supportive Care

The Unique Supportive Care Needs of a Mother With Acute Myeloid Leukemia During Treatment

Tara A. Albrecht
AnnMarie Lee Walton
Ashley Leak Bryant
CJON 2015, 19(1), 16-19 DOI: 10.1188/15.CJON.16-19
Acute myeloid leukemia (AML) is an aggressive cancer of the blood that is linked with poor survival. The disease requires immediate intensive chemotherapy treatment that leaves patients hospitalized for at least one month and often longer, depending on their supportive care needs. Mothers...
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Article

Impact of Clinical and Subclinical Hypersensitivity to Asparaginase in Acute Lymphoblastic Leukemia

Barbara L. Asselin
Vicki Fisher
CJON 2014, 18(6), E107-E112 DOI: 10.1188/14.CJON.E107-E112
Asparaginase is an essential element of acute lymphoblastic leukemia treatment. It depletes serum asparagine (an amino acid necessary for synthesis of cellular proteins), deprives leukemic blast cells of asparagine, and eventually results in cell death. To gain benefit from asparaginase, asparagine...
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