Background: Cancer-related fatigue (CRF) is the most common stressful side effect caused by cancer and cancer treatments. Although CRF causes a significant burden to quality of life, no pharmacologic interventions are available because the mechanism remains unknown. Objectives: This systematic...

Pedigree construction is an important component of cancer risk assessment and comprehensive genetic care. Pedigrees must be updated and reevaluated on a regular basis. Complete pedigrees are needed to select genetic tests and interpret genetic testing results accurately, as well as to enroll...

The discovery of driver mutations in non-small cell lung cancer (NSCLC) has led to the advent of targeted therapy and changed the clinical landscape. ROS1 is a rare driver mutation found in 1%–2% of patients diagnosed with NSCLC. This case highlights a young woman of Asian descent with no history...

Gastric cancer is a major cause of cancer-related mortality worldwide and is thought to be responsible for about 10% of cancer-related deaths across the globe. A small proportion of all gastric cancers arise because of a known hereditary syndrome, the most common of which is hereditary diffuse...