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Cancer Constipation: Clinical Summary of the ONS Guidelines™ for Opioid-Induced and Non–Opioid-Related Cancer Constipation

Kristine B. LeFebvre
Barbara Rogers
Brenda Wolles
CJON 2020, 24(6), 685-688 DOI: 10.1188/20.CJON.685-688
Constipation is a prevalent and distressing symptom affecting people with cancer. It may be a chronic condition, or it may be caused by the effects of the disease, its treatment, or the side effects of symptom management, including the use of opioids. These evidence-based guidelines can assist...
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ONS Guidelines Article

ONS Guidelines™ for Opioid-Induced and Non–Opioid-Related Cancer Constipation

Barbara B. Rogers
Pamela K. Ginex
Allison Anbari
Brian J. Hanson
Kristine B. LeFebvre
Rachael Lopez
Deborah M. Thorpe
Brenda Wolles
Kerri A. Moriarty
Christine Maloney
Mark Vrabel
Rebecca L. Morgan
ONF 2020, 47(6), 671-691 DOI: 10.1188/20.ONF.671-691
Purpose: This evidence-based guideline intends to support clinicians, patients, and others in decisions regarding the treatment of constipation in patients with cancer. Methodologic Approach: An interprofessional panel of healthcare professionals with patient representation prioritized clinical...
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ONS Guidelines Article
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Management of Opioid-Induced and Non–Opioid-Related Constipation in Patients With Cancer: Systematic Review and Meta-Analysis

Pamela K. Ginex
Brian J. Hanson
Kristine B. LeFebvre
Yufen Lin
Kerri A. Moriarty
Christine Maloney
Mark Vrabel
Rebecca L. Morgan
ONF 2020, 47(6), E211-E224 DOI: 10.1188/20.ONF.E211-E224
Problem Identification: A systematic review and meta-analysis was conducted to inform the development of national clinical practice guidelines on the management of cancer constipation. Literature Search: PubMed ® , Wiley Cochrane Library, and CINAHL ® were searched for studies published from May...
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ONS Guidelines Article

Supplementary Material for ONS Guidelines™ for Opioid-Induced and Non-Opioid-Related Cancer Constipation

ONF 2020, 1-129 DOI:
Table of Contents Guideline panel conflict of interest disclosures PICO questions Evidence-to-Decision Frameworks Prophylactic bowel regimen and lifestyle education vs. lifestyle education for opioid-induced constipation Osmotic or stimulant laxatives and lifestyle education vs. lifestyle education...
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ONS Guidelines Article

Supplementary Material for ONS Guidelines™ Management of Opioid-Induced and Treatment-Related Constipation: Systematic Review and Meta-Analysis

ONF 2020, 1-51 DOI:
Table of Contents PICO questions Search strategies Evidence risk of bias figure Evidence Profiles Bowel regimen and lifestyle education vs. lifestyle education for opioid-induced constipation Osmotic PEG and lifestyle education vs. lifestyle education for opioid-induced constipation...
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