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Article

The Process of Clinical Trials: A Model for Successful Clinical Trial Participation

Cecile A. Lengacher
Lois Gonzalez
Rosemary Giuliano
Mary P. Bennett
Charles E. Cox
Douglas S. Reintgen
ONF 2001, 1115-1120 DOI:
Purpose/Objectives: To present barriers and strategies related to successful clinical trial participation and integrate them into a model for successful trial participation. Data Sources: The proposed model was developed based on a literature review related to clinical trial participation, review...
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Article

Nurses’ Attitudes Toward Clinical Trials at a Comprehensive Cancer Center

Caroline B. Burnett
Lynda Pixley
Leslie E. Blumenson
Yi Ting Hwang
Neal J. Meropol
ONF 2001, 1187-1192 DOI:
Purpose/Objectives: To identify nurses' attitudes and beliefs toward cancer clinical trials and their perceptions about factors influencing patients' participation in these trials. Design: Descriptive. Setting: National Cancer Institute-designated comprehensive cancer center. Sample: 417 nurses...
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Article

Backing and Forthing: The Process of Decision Making by Women Considering Participation in a Breast Cancer Prevention Trial

Karen Moore Schaefer
Elisabeth Ladd
Mary Ann Gergits
Lorraine Gyauch
ONF 2001, 703-709 DOI:
Purpose/Objectives: To describe the process of decision making by women considering participation in a breast cancer prevention trial (BCPT). Design: Qualitative. Setting/Sample: Twenty-six women considering participation in a BCPT in the Northeastern United States. Methods: Women were interviewed...
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Commentary

Disparities in Hispanic Care

Marjorie Petty
CJON 2019, 23(3), 235 DOI: 10.1188/19.CJON.235
Attendees at a 2019 ONS Congress session about disparities in clinical trials seemed to be aware that African Americans are underrepresented. But what about Hispanic patients with cancer? I sensed that some of my colleagues had not considered Hispanic recruitment before and were surprised to learn...
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Article

CAR T-Cell Therapy: Update on the State of the Science

Misty Lamprecht
Colleen Dansereau
CJON 2019, 23(2), 6-12 DOI: 10.1188/19.CJON.S1.6-12
Background: Chimeric antigen receptor (CAR) T-cell therapy leverages the power of the patient’s own immune system by serving as a bridge to connect genetically modified T cells to the surface antigens of tumor cells based on targeted ligands. Clinical trials have demonstrated compelling overall...
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