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CNE Article

Antiemetic Guidelines: Using Education to Improve Adherence and Reduce Incidence of CINV in Patients Receiving Highly Emetogenic Chemotherapy

Corrine Mellin
Mallory Lexa
Ashley Leak Bryant
Susie Mason
Deborah K. Mayer
CJON 2018, 22(3), 297-303 DOI: 10.1188/18.CJON.297-303
Background: With the development of increasingly effective antiemetic regimens, guideline adherence can prevent 70%–80% of chemotherapy-induced nausea and vomiting (CINV) in patients with cancer. Objectives: This quality improvement project aims to increase rates of adherence to national guidelines...
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Essentials

Chemoprevention: An Overview of Pharmacologic Agents and Nursing Considerations

Jean E. Boucher
CJON 2018, 22(3), 350-353 DOI: 10.1188/18.CJON.350-353
Cancer chemoprevention involves the use of synthetic and biologic agents as targeted therapies for disease prevention, reduction, or suppression. Mechanisms of blocking or suppressing cancer-related pathways include processes of carcinogenesis, chronic inflammatory responses, DNA modulation, and...
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Article

Prevalence, Severity, and Self-Reported Characteristics of Taste Alterations in Patients Receiving Chemotherapy

Sara Campagna
Silvia Gonella
Riccardo Sperlinga
Piero Luigi Giuliano
Rosella Marchese
Rebecca Pedersini
Paola Berchialla
Valerio Dimonte
ONF 2018, 45(3), 342-353 DOI: 10.1188/18.ONF.342-353
Objectives: To describe the prevalence, severity, and self-reported characteristics of taste alterations (TAs) induced by chemotherapy and to investigate TAs across chemotherapy regimens. Sample & Setting: 243 adult patients from five outpatient practices in Northern Italy. Methods &...
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Online Exclusive Article

Cisplatin-Based Therapy and CINV: Optimal Antiemetics During Germ Cell Testicular Cancer Treatment

Meghan Mastrangelo
CJON 2018, 22(2), E31-E36 DOI: 10.1188/18.CJON.E31-E36
Background: Cisplatin-based chemotherapy regimens are the backbone of chemotherapy for germ cell testicular cancer. Cisplatin is administered for five days, causing an overlap of acute and delayed chemotherapy-induced nausea and vomiting (CINV). Although CINV is widely researched, studies involving...
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CNE Article

Nephrotoxicity: Evidence in Patients Receiving Cisplatin Therapy

Elizabeth A. Duffy
Wendy Fitzgerald
Kelley Boyle
Radha Rohatgi
CJON 2018, 22(2), 175-183 DOI: 10.1188/18.CJON.175-183
Background: Cisplatin has been used as a chemotherapeutic agent to treat many different cancers. A well-known side effect of cisplatin is nephrotoxicity, which is the primary dose-limiting toxicity. Hydration in conjunction with appropriate diuresis can decrease the incidence of nephrotoxicity...
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